Tomohiro Koga Senior Assistant Professor

Speciality / Research theme / Keywords
Collagen diseases, Allergology, ImmunologySupervision
Masters ProgrammeDoctoral ProgrammeQualifications
- Doctor of Medicine (Nagasaki University)
- Medical license
Personal/work Web page addresses
http://www.med.nagasaki-u.ac.jp/intmed-1/
Research gate account links
https://www.researchgate.net/profile/Tomohiro_Koga
Affiliation(s)
- Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
- Nagasaki university hospital, Medical education development center
Background
- April 2005 – March 2009 National Organization Hospital Organization Nagasaki Medical Center
- April 2009 – May 2011 Nagasaki University Hospital Department of rheumatology
- June 2011 – February 2014 Harvard Medical University (Beth Israel Deaconess Medical Center, Rheumatology Division, Dr. Tsokos Lab), research fellow
- March 2014 – November 2016 Nagasaki University Hospital Medical Education Development Center, assistant professor
- December 2016 – present Center for Bioinformatics and Molecular Medicine, Nagasaki University Graduate School of Biomedical Sciences, assistant professor (the Leading Initiative for Excellent Young Researchers of the Ministry of Education, Culture, Sports, Science and Technology)
Teaching
Diagnostics: practical training on collagen diseasesEducation for medical intern
Research
- Studies on T cell signaling in autoimmune diseases
- Research on gene analysis and cytokine analysis in autoinflammatory diseases
The country/countries where you work currently
Japan
Five MOST IMPORTANT/INTERESTING recent publications
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Otsuka M, Koga T (corresponding author), Sumiyoshi R, Fukui S, Kaneko Y, Shimizu T, Katsube A, Yano S, Masaki Y, Ide M, Yoshifuji H, Kitano M, Sato Y, Sawa N, Niiro H, Nakamura N, Fajgenbaum DC, van Rhee F, Kawakami A. Exploring the Clinical Diversity of Castleman Disease and TAFRO Syndrome: A Japanese Multicenter Study on Lymph Node Distribution Patterns. Am J Hematol. 2025; 100(4):592-605.
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Koga T, Kita K, Okumura J, Yoshiura KI, Kawakami A. A novel frameshift mutation in ADCK1 identified in a case of chronic fatigue syndrome successfully treated with oral 5-ALA/SFC. Immunol Med. 2024; 26:1-5.
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Koga T, Sumiyoshi R, Tsuji Y, Kodama K, Endo Y, Furukawa K, Kawakami A. Efficacy and safety of 5-aminolevulinic acid in adult-onset Still’s disease: A preclinical study in mice and a pilot study in humans. Clin Immunol. 2023;257:109846.
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Harada T, Kikushige Y, Miyamoto T, Uno K, Niiro H, Kawakami A, Koga T, Akashi K, Yoshizaki K. Peripheral helper-T-cell-derived CXCL13 is a crucial pathogenic factor in idiopathic multicentric Castleman disease. Nat Commun. 2023;14(1):6959.
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Koga T, Umeda M, Yoshida N, Satyam A, Jha M, Scherlinger M, Bhargava R, Tsokos MG, Sato T, Furukawa K, Endo Y, Fukui S, Iwamoto N, Abiru N, Okita M, Ito M, Kawakami A, Tsokos GC. Inhibition of calcium/calmodulin-dependent protein kinase IV in arthritis: dual effect on Th17 cell activation and osteoclastogenesis. Rheumatology (Oxford). 2023;62(2):861-871.
Message
As a clinician with researchers’ eyes, we are conducting research that can contribute to practical use for patients based on clinical questions as a rheumatologist. In order to solve the unmet medical needs of autoimmune diseases and autoinflammatory diseases which are regarded as rare intractable diseases, we are looking for fellows who can study together.