Assistant Professor Takaya Sakura

Speciality / Research theme / Keywords

Parasitology, Molecular Biology, Cellular Biology

Supervision

Masters ProgrammeDoctoral Programme

Personal/work Web page addresses

https://researchmap.jp/-2qE3_xt?lang=ja
https://orcid.org/0000-0002-8320-8485
http://www.tm.nagasaki-u.ac.jp/molecdyna/

Research gate or Linked-in account links

https://www.researchgate.net/profile/Takaya-Sakura

Affiliation(s)

Department of Molecular Infection Dynamics, Institute of Tropical Medicine (NEKKEN), Nagasaki University

Background

Ph. D, Nagasaki University, Graduate School of Biomedical Sciences in 2013.

Postdoctoral researcher, National Institute of Infectious Diseases (NIID), Institut Pasteur de Lille, Institut Cochin, Nagasaki University, School of Tropical Medicine and Global Health.

Assistant professor, Department of Molecular Infection Dynamics, Institute of Tropical Medicine (NEKKEN), Nagasaki University from 2019.

Research

Parasitology, Drug Discovery

Five MOST IMPORTANT/INTERESTING recent publications

1. Komatsuya K^†,  Sakura T^†, Shiomi K, Ōmura S, Hikosaka K, Nozaki T, Kita K, Inaoka DK. Siccanin Is a Dual-Target Inhibitor of Plasmodium falciparum Mitochondrial Complex II and Complex III. Pharmaceuticals (Basel). 2022; 15(7):903. (^† contributed equally)
2. Fukumoto J, Sakura T, Matsubara R, Tahara M, Matsuzaki M, Nagamune K. Rhoptry kinase protein 39 (ROP39) is a novel factor that recruits host mitochondria to the   parasitophorous vacuole of Toxoplasma gondii. Biol Open. 2021; 10(9):bio058988.
3. Hartuti ED, Sakura T, Tagod MSO, Yoshida E, Wang X, Mochizuki K, Acharjee R, Matsuo Y, Tokumasu F, Mori M, Waluyo D, Shiomi K, Nozaki T, Hamano S, Shiba T, Kita  K, Inaoka DK. Identification of 3,4-Dihydro-2H,6H-pyrimido[1,2-c][1,3]benzothiazin-6-imine Derivatives as Novel Selective Inhibitors of Plasmodium falciparum          Dihydroorotate Dehydrogenase. International Journal of Molecular Sciences. 2021; 22(13):7236.
4. Sakurai Y, Ngwe Tun MM, Kurosaki Y, Sakura T, Inaoka DK, Fujine K, Kita K, Morita K, Yasuda J. 5-amino levulinic acid inhibits SARS-CoV-2 infection in vitro.  Biochemical and Biophysical Research Communications. 2021; 545:203-207.
5. Sakura T, Sindikubwabo F, Oesterlin LK, Bousquet H, Slomianny C, Hakimi MA, Langsley G, Tomavo S. A Critical Role for Toxoplasma gondii Vacuolar Protein Sorting VPS9 in Secretory Organelle Biogenesis and Host Infection. Scientific Reports. 2016; 6:38842.