取得学位・資格

M.D.(Japan), DTM&H (London), MSc Clinical Tropical Medicine (London), PhD (U.K.)

個人/所属ウェブページ

http://www.tm.nagasaki-u.ac.jp/internal/nekkennaika.htm

連絡先

kari@nagasaki-u.ac.jp

他所属

• Department of Clinical Medicine, Institute of Tropical Medicine (NEKKEN)
• Department of Infectious Diseases, Nagasaki University Hospital
• School of Tropical Medicine and Global Health, Nagasaki University
• Honorary Professor, Clinical Research Department, Faculty of Infectious Tropical Medicine, London School of Tropical Medicine and Hygiene, UK

経歴

I had my residency training in internal medicine in Tokyo, 1986-1988. From those days I was interested in working in Africa, which let me do DTMH in London, followed by a post-graduate clinical training in Harare Central Hospital, Zimbabwe, 1989 where I encountered my life work, AIDS. My master project on HIV viral load at LSHTM in 1990 was very successful that I was offered a job as a clinical research fellow at the Jefferiss Wing, St. Mary’s Hospital. My asset of multi-disciplinary human-network has been established when working in London, Oxford and West Africa for 8 years as well as in Tokyo at NIID for 3 years and in Thailand for JICA for 4 years.

教育活動

I am the course director of Master of Tropical Medicine (MTM) where I teach clinical tropical medicine, malaria and non-malaria febrile illness, STD and HIV/AIDS. I also facilitate the tropical infectious disease case discussion.

As a chief of NEKKEN training/education center, I also organize the three-month diploma course of tropical medicine.

研究活動

HIV research had been a core of my carrier before joining NEKKEN. It broadened my skills to understand a disease from multidisciplinary aspects such as behavioral, epidemiological, clinical science, molecular immunology and virology. Most of my work has derived from clinical-epidemiology settings such as cohort or case-control studies. I enjoy digging out clinical research questions by seeing patients and discussing with medical professionals. On joining to the current group of NEKKEN, my research topic has been broaden toward pneumonia in low, middle and high-income countries, non-malarial febrile illness such as typhus, leptospirosis. Now we have on-going studies in infectious disease wards in North Vietnam, the Philippines and Japan.
Discussing in an overcrowded ward in Bac Mai Hospital, Vietnam with Dr. Thuy, one of the most experienced I.D. physicians.

現在の主な研究活動地域

• The Philippines
• Vietnam
• Thailand
• Japan

最近の5つの出版物

1. Saito N, Solante RM, Guzman FD, Telan EO, Umipig DV, Calayo JP, Frayco CH, Lazaro JC, Ribo MR, Dimapilis AQ, Dimapilis VO, Villanueva AM, Mauhay JL, Suzuki M, Yasunami M, Koizumi N, Kitashoji E, Sakashita K, Yasuda I, Nishiyama A, Smith C, Ariyoshi K, Parry CM. A prospective observational study of community-acquired bacterial bloodstream infections in Metro Manila, the Philippines. PLOS Neglected Tropical. 2022; 16(5):e0010414.
2. Dhoubhadel BG, Suzuki M, Ishifuji T, Yaegashi M, Asoh N, Ishida M, Hamaguchi S, Aoshima M, Yasunami M, Ariyoshi K, Morimoto K. High prevalence of multiple serotypes of pneumococci in patients with pneumonia and their associated risk factors. Thorax. 2022; 77(11):1121-1130.
3. Katoh S, Cuong NC, Hamaguchi S, Thuy PT, Cuong DD, Anh LK, Anh NTH, Anh DD, Sando E, Suzuki M, Fujita H, Yasunami M, Yoshihara K, Yoshida LM, Paris DH, Ariyoshi K. Challenges in diagnosing scrub typhus among hospitalized patients with undifferentiated fever at a national tertiary hospital in northern Vietnam. PLOS Neglected Tropical Diseases. 2019; 13(12):e0007928.
4. Yanagisawa K, Wichukchinda N, Tsuchiya N, Yasunami M, Rojanawiwat A, Tanaka H, Saji H, Ogawa Y, Handa H, Pathipvanich P, Ariyoshi K, Sawanpanyalert P. Deficiency of mannose-binding lectin is a risk of Pneumocystis jirovecii pneumonia in a natural history cohort of people living with HIV/AIDS in Northern Thailand. PLoS One. 2020; 15(12): e0242438.
5.  Yamashita Y, Oe T, Kawakami K, Osada-Oka M, Ozeki Y, Terahara K, Yasuda I, Edwards T, Tanaka T, Tsunetsugu-Yokota Y, Matsumoto S, Ariyoshi K. CD4⁺ T Responses Other Than Th1 Type Are Preferentially Induced by Latency-Associated Antigens in the State of Latent Mycobacterium tuberculosis Infection.  Frontiers in Immunology. 2019; 10:2807.

他の出版物へのリンク

http://www.ncbi.nlm.nih.gov/sites/myncbi/1n5JSXaavr65l/bibliography/48630402/public/?sort=date&direction=ascending

メッセージ

1992年より６年間，英国MRCガンビア研究所でエイズ研究と研究所附属病院での臨床を経験，このときの国際的人脈が財産。帰国後は４年間タイに滞在し，タイ人エイズ研究者の育成に努めた。2005年長崎大学教授就任後は，主にベトナム，フィリピンでの臨床疫学研究を推進しつつ，長崎大学病院では感染症内科（熱研内科）科長として内科診療に従事。また，熱研教育室長，長崎大学熱帯医学・グローバルヘルス研究科副研究科長として熱帯医学教育に広く携わる。日本よりはるかに難しい課題を抱えた途上国の医療保健現場で役に立ちたいと思うのなら，さらに努力して勉強する気概をもって欲しい。